tag:blogger.com,1999:blog-5002675950760488813.post3290475833906205745..comments2024-01-21T14:11:10.779-08:00Comments on The Unsilenced Science: Genes Dealt Made Asians Sveltenooffensebuthttp://www.blogger.com/profile/02461190919466049463noreply@blogger.comBlogger9125tag:blogger.com,1999:blog-5002675950760488813.post-66368876946387923912014-08-21T14:14:12.130-07:002014-08-21T14:14:12.130-07:00A group that included Daniel Belsky, who was from ...A group that included Daniel Belsky, who was from the team that originally used the genetic risk index on individuals, as mentioned in my post, <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081643/" rel="nofollow">recently used it</a> on white and black individuals. The index created from whites worked on blacks, though not quite as well. This genetic approach is still at an early stage. As more alleles are identified, the predictive ability will probably increase in different racial and ethnic groups. So, the apparent discrepancy between genetic risk and high obesity rates among Mexicans and African-American women (compared to African-American men) could be due to both culture/environment/nurture and weakness in the genetic index.nooffensebuthttps://www.blogger.com/profile/02461190919466049463noreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-31730998142042882452014-08-21T13:12:11.897-07:002014-08-21T13:12:11.897-07:00I'm surprised that the Mexican genetic risk fo...I'm surprised that the Mexican genetic risk for obesity is rather low, even close to Asian levels, considering their high obesity rates both in America and in Mexico itself. Do you think then that their weight issues are also largely cultural? Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-30271455344795247892012-12-01T11:24:21.338-08:002012-12-01T11:24:21.338-08:00"adult black women have nearly twice the prev..."adult black women have nearly twice the prevalence of obesity as adult white women, but for the men no statistically significant difference exists. Therefore, I suspect that the unfortunate obesity epidemic among African-American women is a cultural phenomenon, rather than genetic destiny. "<br /><br />It could be a nutrition problem too. Women and men have sex-specific nutritional requirements and cravings. If the "typical" black american diet provides for the men's cravings on par with the typical white american diet, but does not do so for the women's cravings, another possibility would be obvious.<br /><br />Differentials in living areas and access to nutritious food (due to the "food dessert" effect, or to wage variations) aren't cultural so much as societal.Robert Evansnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-85139951253854941452012-09-28T10:42:56.594-07:002012-09-28T10:42:56.594-07:00Thank you for bringing that to my attention. I sh...Thank you for bringing that to my attention. I shall be writing again about MAOA in the near future.nooffensebuthttps://www.blogger.com/profile/02461190919466049463noreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-86965534157309427432012-09-28T03:36:55.307-07:002012-09-28T03:36:55.307-07:00I came across this study/link and immediately thou...I came across this study/link and immediately thought of your writings on MAOA.<br /><br />http://www.sciencedirect.com/science/article/pii/S0191886912004047Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-5141446008640828062012-09-22T12:28:03.329-07:002012-09-22T12:28:03.329-07:00Magnificent! (As usual. :-P )Magnificent! (As usual. :-P )Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-17713050543343594282012-09-18T19:58:22.497-07:002012-09-18T19:58:22.497-07:00Some day, people will look back at this blog and w...Some day, people will look back at this blog and wonder why our society, for so long, made talking about these issues the purview of anonymous bloggers.<br /><br />You, sir, are doing the Lord's work. <br /><br />Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-82553708631328410322012-09-13T21:06:37.994-07:002012-09-13T21:06:37.994-07:00ASPM implicated in Cetacean brain size as well<a href="http://johnhawks.net/weblog/reviews/brain/cetacean-aspm-selection-yong-2012.html" rel="nofollow">ASPM implicated in Cetacean brain size as well</a>Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5002675950760488813.post-75758588591595924602012-09-10T08:08:11.892-07:002012-09-10T08:08:11.892-07:00I see reason to doubt that even with your limited ...I see reason to doubt that even with your limited set of loci it is meaningful to estimate genetic risks across ethnic populations where the source data is based on one ethnicity.<br /><br />You've reduced one source of error, but you've still left another: Asian-specific obesity alleles will be missed as may alleles common in Asians but rare in Europeans. Moreover, the detectability threshold of the GWAS studies will bias the identification of genes to those common in European populations, that these genes are slightly less common in Asians, therefore, may be simply an artefact of their method of identification.Jacknoreply@blogger.com